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“We’re not there yet, but we’re getting there on the uphill side.” 1 Preclinical data on the combination of amylin and GLP-1 analogs in non-human primates and rodents indicated greater reductions in food intake and body weight by targeting fat mass while preserving lean mass and reducing metabolic adaptation
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All clamp experiments were performed at the National Mouse Metabolic Phenotyping Center at UMass Medical School
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