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[DOI] [PubMed] [Google Scholar] 191.Storck EM, Özbalci C, Eggert US
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Drugs much smaller have low oral bioavailability due to difficulty in getting through the gut wall… Even if AOD9604 was only a small peptide, it would still be susceptible to enzymatic degradation in the gut, being derived as it is from a naturally occurring protein12
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