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Therapeutic significance of β-glucuronidase activity and its inhibitors: A review - ScienceDirect
142,661,666 For instance, promoters for the activator AtzR derived from cellular experiments had background expression in CFE in the absence of analyte and needed to be reoptimized in the cell-free environment
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A simplified framework has divided macrophages into two polarized states that can be reproducibly induced in vitro: classically-activated pro-inflammatory M1 macrophages, which are induced by Toll-like receptor (TLR) agonists such as lipopolysaccharide and IFNγ, and alternatively-activated anti-inflammatory M2 macrophages, induced by IL-4 and IL-13 [138]
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