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Data are presented as Mean ± SEM (n = 6)
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Histological Imaging/Staining In Vivo Efficacy Study Histological Imaging/Staining RT-PCR ELISA Biological Activity Description IC 50 & Target EC50: 99 nM (FXR) Cellular Effect In Vitro Obeticholic acid (INT-747) increases the expression of FXR-regulated genes in rat hepatocytes [1]
such as cataracts and mitochondrial degeneration.
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