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GHK-Cu, in concentrations of 0.1–10 micromolar, increased expression of epidermal stem cell markers such as integrins and p63 in basal keratinocytes in dermal skin equivalents, which according to the authors indicate increased stemness and proliferative potential of basal keratinocytes
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So I would hazard a guess to say it's unlikely that the bortezomib is the main culprit behind the kidney failure
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