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The Grx family of proteins plays a key role in the regulation of glutathionylation reactions ( Figure 3

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This is because, like many antidepressants, supplementary 5-HTP raises the amount of serotonin in the brain, so the combination could result in dangerous levels of the neurotransmitter.8 39 With that being said, let’s take a look at how 5-HTP’s ability to boost serotonin could be beneficial for those dealing with PMDD