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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice - PMC
After the acute repletion phase, therapy is usually transitioned to an oral maintenance multivitamin containing a physiological dose of pyridoxine (2-5 mg daily) for several weeks, along with dietary counseling to prevent recurrence
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Sikiric and colleagues reviewed the compound in Curr Med Chem in 2012
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