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High-Risk Empiric Antibiotic Therapy Single agent with Imipenem-cilastatin 500mg IV every 6 hours OR Meropenem 1g IV every 8 hours OR Doripenem 500mg IV every 8 hours OR Piperacillin-tazobactam 4.5g IV every 6 hours Combination of one of the following with 500mg of IV or PO Metronidazole every 8 hours Cefepime 2g IV every 8 hours Ceftazidime 2g IV every 8 hours Discharge from Inpatient Patients must also meet certain discharge criteria

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5-Amino-1MQ — 5-amino-1-methylquinolinium iodide, a small-molecule NNMT (nicotinamide-N-methyltransferase) inhibitor — supplied by BioFusion as a vacuum-sealed lyophilized 10mg vial for NNMT-pathway and methyl-donor-research chemistry