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Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases | Encyclopedia MDPI
doi: 10.1002/hep.24132
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Other factors proposed in the pathogenesis of IBD include an initial breakdown of the epithelial barrier which can lead to a self-amplifying cycle of immune activation and cytokine release [79], and loss of tolerance to endogenous microflora and dietary antigens [82,87]
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