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Here are some important data points from recent reviews: A 2023 review identified 106 active clinical trials involving glutathione across many health conditions, but only 12 involved cancer None of those 12 cancer trials tested glutathione alone as a definitive cancer treatment A systematic review of 19 antioxidant trials included only 7 that studied glutathione specifically In one trial, 58% of patients using glutathione completed chemotherapy compared to 39% in the control group Two of six glutathione trials showed statistically significant reductions in neurotoxicity, with strong p-values of 0.0001 and 0.01 These numbers show promise in narrow situations

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However, careful optimization of dosage, sequencing, and delivery methods is required to attain clinically significant results