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PADI-dependent mitochondrial adaptation drives resistance to KRAS inhibitors: Cell Reports
Keywords: immune checkpoint inhibitors, skin toxicity, adverse effects, nivolumab, pembrolizumab, ipilimumab Introduction Checkpoint Inhibitor Mode of Action Checkpoint inhibitors (CPIs) are molecules that increase the endogenous immune response against tumors by blocking receptors responsible for lymphocyte inactivation
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Further animal and in vitro studies suggest that epithalon may inhibit breast adenocarcinoma, linked to its telomerase activity [5]
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