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The integration of advanced techniques like in vivo microdialysis (El Rawas et al., 2009), Magnetic Resonance Imaging (MRI) (Nag et al., 2009), and molecular biology methods, such as immunohistochemistry (Herring et al., 2009) provided a mechanistic understanding of how EE impacts neural circuits involved in various brain functions, offering new insights into its potential therapeutic applications

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identified IR775, an efficient NIR hydrophobic ICG analog, that can achieve combinatorial phototherapy with a single phototherapy agent