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EPO is an essential hormone that’s secreted by the kidney in response to cellular hypoxia (decreased oxygen) and it stimulates RBC production
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As a transmembrane glycoprotein with receptor-mediated adhesion function and ectoenzymatic activity, CD38 is ubiquitously expressed on MM cells, as well as some regulatory T cells (Tregs) and natural killer (NK) cells [5, 6]
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