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That makes cagrilintide less of a direct competitor and more of a potential alternative for people whose bodies don’t respond well to GLP-1 therapy, or who struggle with its side effects
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Mapping and perturbing these contact-site hubs—with compartment-targeted reporters, localized inhibitors/knockdowns and super-resolution/functional imaging—is essential for experimental design and for therapies that aim to modulate redox outcomes without blunting beneficial signalling (Leo et al
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