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✓ 🩸 CYP3A4 requires heme iron and NADPH-cytochrome P450 reductase, generating reactive intermediates that can cause hepatotoxicity
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Animal studies show the peptide can recruit the azygos vein system during caval vein occlusion, parasagittal veins for compromised brain circulation, and pancreaticoduodenal arteries when mesenteric vessels become blocked
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